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Research

What I work on

My work sits at the intersection of medical image processing and machine learning, focused on making perfusion MRI a more objective tool for neuro-oncology.

01

Quantitative DCE-MRI

Perfusion imaging of brain tumors to derive objective, reproducible biomarkers for grading and treatment assessment.

02

Vessel Segmentation

Swin UNETR, Attention U-Net and U-Net pipelines for automatic segmentation of large blood vessels in tumor MRI.

03

Glioma Classification

Differentiating glioblastoma, diffuse midline glioma and grade-3 glioma from quantitative perfusion parameters.

04

Radiomics & Texture

PyRadiomics workflows — 107 features per sequence, 851 with wavelet decomposition — paired with ML classifiers.

05

MRI Contrast Agent Optimization

Collaborative work with IIT Mandi — MRI scanning of contrast-agent samples (n = 27) and T1/T2 relaxivity computation for selecting optimal agents for specific MRI applications.

06

Brain–Computer Interfaces

EEG-based study of advertisement impact on consumer preference and mental stress detection, using SVM classification (M.Tech research).

Featured Project

Removing vascular bias from tumor perfusion maps

Pipeline: T1/T2/PD and dynamic MRI through perfusion processing to CBV and Slope-2 maps, k-means clustering of CBVSlope2, and LBV mask generation with manual refinement.

Pipeline overview — Pipeline overview — multiparametric MRI → perfusion maps (CBV, Slope-2) → k-means clustering of the CBV×Slope-2 product → generated LBV mask, refined to ground truth.

Problem

Large intra- and peri-tumoral blood vessels distort quantitative DCE-MRI perfusion maps, making glioma grading operator-dependent and hard to reproduce.

Method

A Swin UNETR transformer segments large vasculature from brain-tumor DCE-MRI — benchmarked against Attention U-Net and U-Net — then masks it out of the perfusion computation.

Result

More reproducible perfusion estimates and cleaner grade separation — published in Magnetic Resonance Imaging (2025) and presented as a Power Pitch at ISMRM.

Read the paper — Magnetic Resonance Imaging (2025)
Methods & Tools

Technical toolkit

Imaging
DCE-MRICTMedical Image Processing
Languages
PythonMATLAB
Deep Learning
CNNU-NetAttention U-NetSwin UNETR
Machine Learning
SVMLogistic RegressionDecision TreeRandom ForestKNN
Clustering
k-meansGMMFCM
Tools
PyRadiomicsImageJSPMMRIcronRadiAnt